Head of DeFi

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Head of DeFi based in United States. This is a senior commercial leadership role working closely with executive and product leadership to drive growth across a DeFi-focused product portfolio. You’ll lead partnerships, DeFi integrations, strategic alliances, and business development initiatives across the broader on-chain financial ecosystem. The role combines commercial strategy with hands-on relationship building, market intelligence, deal execution, and product feedback. You’ll engage directly with crypto-native funds, DeFi curators, protocol founders, and other ecosystem participants to identify and develop high-value opportunities. Your understanding of liquidity, TVL, lending, borrowing, DEXs, stablecoins, governance, and on-chain capital flows will inform both partnerships and product strategy. This is an entrepreneurial, high-ownership environment suited to someone who can operate independently, build relationships quickly, and turn strategic opportunities into measurable growth.